Diets High In Choline (Eggs) Raise Risk For Lethal Prostate Cancer

"Eggs are particularly rich dietary sources of choline and cholesterol, which are highly concentrated in prostate cancer cells, and blood concentrations of both nutrients have been positively associated with risk of advanced prostate cancer," say the authors of this study:

Egg, Red Meat, And Poultry Intake And Risk Of Lethal Prostate Cancer In The Prostate Specific Antigen-era: Incidence And Survival, Cancer Prevention Research, December 2011

So, can eating choline-rich eggs raise the risk for lethal prostate cancer? They found:

"Among 27,607 men followed from 1994 to 2008 ... Men who consumed 2.5 or more eggs per week had an 81% increased risk of lethal prostate cancer compared with men who consumed less than 0.5 eggs per week.
...
In conclusion, we observed a nearly two-fold increased risk of lethal prostate among men who consumed higher amounts of eggs."

Maybe it can. Does that mean that other choline-rich foods also increase the risk for lethal prostate cancer?

Choline Intake And Risk Of Lethal Prostate Cancer: Incidence And Survival, American Journal of Clinical Nutrition, October 2012

OBJECTIVE: Our objective was to examine whether dietary choline, choline-containing compounds, and betaine (a choline metabolite) increase the risk of lethal prostate cancer.

DESIGN: We prospectively examined the intake of these nutrients and the risk of lethal prostate cancer among 47,896 men in the Health Professionals Follow-Up Study.

RESULTS: In the incidence analysis ... Men in the highest quintile of choline intake had a 70% increased risk of lethal prostate cancer.

CONCLUSION: Of the 47,896 men in our study population, choline intake was associated with an increased risk of lethal prostate cancer.

Maybe it does.

Looks like eggs, and the chickens from whence they came, and the eggs from whence they came, and the ... are the best sources for choline:*



* The Daily Value for choline is 550 mg.
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