I wonder what's happening to all that drool.
Maybe it's going into their recent campaign to warn would-be consumers about the drug's untoward side effects (see bulleted list). The latest public rumble in GSK's struggle to get Alli on store shelves has been their outreach to pharmacists. Reuters is reporting that GSK met with pharmacists at Walgreens (the biggest US drugstore chain by revenue) in the beginning of October to, as one pharmacist described, "get them on board."
"If a patient experiences these unpleasant side effects, they will likely discontinue use."Can't have that.
- Jennifer McFee, Walgreens pharmacist
Drugstore.com is selling a one-month supply of prescription Xenical, 90 capsules, for $204.40. Alli is expected to cost about a third of that price. However, Xenical is a 120 mg strength tablet, Alli is only 60 mg. Also, where Xenical may be covered by insurance, Alli will be an out-of-pocket expense.
The active ingredient in both Xenical and Alli works by interfering with the action of the enzyme lipase which is integral in the digestion and consequently absorption of fat. The pills are taken with meals that contain fat. About 20 to 30% of the fat in those meals goes out with the stool.
Stools that contain a substantial amount of fat can, well, be a nuisance. They create a feeling of urgency, and ... loss of control. They leak. They are fetid. They float, and so resist attempts to flush. Their movement is accompanied by copious quantities of gas. The fat they contain is not always fat you want to get rid of. Vitamins A (and beta-carotene), E, D, and K are fats. Alpha-linolenic acid (ALA) and linoleic acid (LA) are essential fats that we absolutely need and can only get in food. The famous, and justifiably so, EPA and DHA, are types of omega-3 fats that studies show keep our blood flowing and our mood glowing.
All those goods fats and more ... out the back door. For what? Less than 1 pound a month?1 And a $70-a-month habit for life? Let me suggest a more nutritious, less annoying, and more economical therapy - walking.
- Xenical product insert (pdf)
This post is for K, she of the iron intestines.