High Dose Zinc Increases Hospital Admissions Due to Genitourinary Complications, The Journal of Urology, 2007
In this randomized, placebo-controlled study of 3,640 men and women:
"We found a significant increase in hospital admissions due to genitourinary causes in patients on zinc* vs nonzinc formulations."* Patients were taking 80 mg zinc/day.
"The risk was greatest in male patients."
The most common causes of hospital admission:
- Benign prostatic hyperplasia/urinary retention
- Urinary tract infection ("When comparing zinc to placebo, significant increases in urinary tract infections were found.")
- Urinary lithiasis (kidney stones)
- Renal failure
"Zinc supplementation at high levels results in increased hospitalizations for urinary complications compared to placebo."